SYDNEY,
Australian surgeons
said Friday they have used hearts which had stopped beating in
successful transplants, in a world first they said could change the way
organs are donated.
Until now, doctors have relied on
using the still-beating hearts of donors who have been declared brain
dead, often placing the recovered organs on ice and rushing them to
their recipients.
But Sydney's St Vincent's Hospital
and the Victor Chang Cardiac Research Institute have developed a
technique which means hearts which had been still for 20 minutes can be
resuscitated and transplanted into a patient.
So far
three people have received hearts in this way, with two recovering well
and the third and most recent recipient still requiring intensive care.
"They
are the only three in the world," surgeon Kumud Dhital, who is an
associate professor at the University of New South Wales in Sydney, told
AFP.
CIRCULATORY DEATH
"We
know that within a certain period of time the heart, like other organs,
can be reanimated, restarted, and only now have we been able to do it
in a fashion whereby a heart that has stopped somewhere can be retrieved
by the transplant team, put on the machine... and then (surgeons can)
transplant it."
The technique involves donor hearts
being transferred to a portable machine known as a "heart in a box" in
which they were placed in a preservation solution, resuscitated and kept
warm.
Professor Peter MacDonald, medical director of
the St Vincent's Heart Transplant Unit, said the use of hearts "donated
after circulatory death" would make far more available for transplant.
"This breakthrough represents a major inroad to reducing the shortage of donor organs," he said.
Michelle Gribilas, the first patient to receive one of the three hearts, said she was very sick before her operation.
"Now I'm a different person altogether," the 57-year-old said. "I feel like I'm 40 years old. I'm very lucky."
The second recipient, Jan Damen, who had the surgery about two weeks ago, said he felt "amazing".
"I'm not religious or spiritual but it's a wild thing to get your head around," he said.
Dhital
said reanimating hearts using the machine could increase safety for
patients because it gave surgeons confidence that the organ was
functioning.
"I would suggest that in the next five
years or so we will be shifting more and more towards machine
preservation of hearts," he said.
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