Researchers in China have discovered a new type of swine flu
that is capable of triggering a pandemic, according to a study published
Monday in the US science journal PNAS.
Named G4, it is genetically descended from the H1N1 strain that caused a pandemic in 2009.
It
possesses "all the essential hallmarks of being highly adapted to
infect humans," say the authors, scientists at Chinese universities and
China's Center for Disease Control and Prevention.
From
2011 to 2018, researchers took 30,000 nasal swabs from pigs in
slaughterhouses in 10 Chinese provinces and in a veterinary hospital,
allowing them to isolate 179 swine flu viruses.
The majority were of a new kind which has been dominant among pigs since 2016.
The researchers then carried out various experiments including
on ferrets, which are widely used in flu studies because they experience
similar symptoms to humans -- principally fever, coughing and sneezing.
G4
was observed to be highly infectious, replicating in human cells and
causing more serious symptoms in ferrets than other viruses.
Tests also showed that any immunity humans gain from exposure to seasonal flu does not provide protection from G4.
According
to blood tests which showed up antibodies created by exposure to the
virus, 10.4 percent of swine workers had already been infected.
The tests showed that as many as 4.4 percent of the general population also appeared to have been exposed.
The
virus has therefore already passed from animals to humans but there is
no evidence yet that it can be passed from human to human -- the
scientists' main worry.
"It is of concern that human
infection of G4 virus will further human adaptation and increase the
risk of a human pandemic," the researchers wrote.
Asked
about the virus on Tuesday, Chinese foreign ministry spokesman Zhao
Lijian told a regular press briefing that China "has been paying close
attention to its development" and will take all needed action to prevent
its spread and any outbreaks.
The study's authors called for urgent measures to monitor people working with pigs.
"The
work comes as a salutary reminder that we are constantly at risk of new
emergence of zoonotic pathogens and that farmed animals, with which
humans have greater contact than with wildlife, may act as the source
for important pandemic viruses," said James Wood, head of the department
of veterinary medicine at Cambridge University.
A zoonotic infection is caused by a pathogen that has jumped from a non-human animal into a human.
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